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Title: |
Primary Cutaneous Ewing’s Sarcoma/Primitive Neuroectodermal Tumor: Report of the First Case Diagnosed on Aspiration Cytology | |||||||||||||||||||
| Authors: | Sonali Kalra, M.D., Ruchika Gupta, M.D., Sompal Singh, M.D., Kusum Gupta, D.C.P., and Madhur Kudesia, M.D. | |||||||||||||||||||
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Background: Extraskeletal Ewing’s sarcoma (ES) was first recognized as a soft tissue tumor in 1975. Primary cutaneous occurrence of Ewing’s sarcoma/primitive neuroectodermal tumor (ES/PNET) has been reported in only 31 cases so far. To the best of our knowledge, there is no report of preoperative cytologic diagnosis of cutaneous ES/PNET in the available literature except for this one. Case A young adult presented with a recurrent swelling on the medial aspect of the left leg that had been present for the past 5 years. Fine needle aspiration cytology yielded cellular smears showing a small round cell tumor. Immunostaining on cell block material showed positivity for CD99, S-100 protein and neuron-specific enolase. A cytologic diagnosis of primary cutaneous ES/PNET was made. Local excision was performed, and the patient was well after 2 years of follow-up. Conclusion: Primary cutaneous ES/PNET is a rare cutaneous tumor with a favorable clinical outcome. It can be diagnosed on cytology; however, immunocytochemistry is mandatory for differentiation from other small round cell tumors. (Acta Cytol 2010;54:193–196) |
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| Keywords: | aspiration biopsy, fine-needle; primitive neuroectodermal tumor; sarcoma, Ewing’s | |||||||||||||||||||
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