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Title: |
Fine Needle Aspiration of a Breast Mass Caused by Metastatic Ewing’s Sarcoma | |||||||||||||||||||
| Authors: | Bita Geramizadeh, M.D., Alireza Makarempour, M.D., and Amin Abolhassani Foroughi, M.D. | |||||||||||||||||||
| To the Editors: Metastasis to the breast is very rare and unusual and makes up 2.7% of all malignant breast tumors.1 Metastatic disease should be taken into consideration in the differential diagnosis of a tumor of the breast, especially when there is a history of an extramammary malignant neoplasm.2 Common sources of blood-borne metastasis are melanoma, lung carcinoma and lymphoma/leukemia.3 Sarcoma is an extremely rare source of metastasis to the breast.4 Metastasis of Ewing’s sarcoma is very rare, and just 1 case has been reported in the literature.3 Fine needle aspiration of metastatic Ewing’s sarcoma to the breast has not been reported before. Our patient was a 20-year-old female with a history of a right tibial mass. She had undergone above-the-knee amputation, and the diagnosis of Ewing’s sarcoma was made and confirmed by histology, immunohistochemistry and molecular studies (i.e., small cell malignant tumor of bone with diffusely positive MIC-2 and translocation 11, 22). Despite chemoradiotherapy, 2 months later the patient felt a mass in her right breast by self-examination. | ||||||||||||||||||||
| Keywords: | aspiration biopsy, fine-needle; breast cancer; metastasis; sarcoma, Ewing’s | |||||||||||||||||||
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